Annotation Detail

Information
Associated Genes
TNF
Associated Variants
TNF c.-488G>A
TNF c.-488G>A
Associated Disease
cervix carcinoma
Source Database
DisGeNET
Description
Subgroup analysis by the types of cervical lesions showed that there was a significant association between TNF-α rs1800629 polymorphism and increased risk of cervical cancer (For A versus G: OR 1.24, 95%CI 1.05-1.47, P = 0.011; for AA versus GG: OR 1.31, 95%CI 1.01-1.70, P = 0.043; for AA/GA versus GG: OR 1.25, 95%CI 1.01-1.54, P = 0.039).
Pubmed
24015171
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0191640904391783
Year of publication
2013
Drugs