Annotation Detail

Information
Associated Genes
IL6
Associated Variants
IL6 MUTATION
IL6 MUTATION
Associated Disease
Prostatic Neoplasms
Source Database
DisGeNET
Description
Together with our previous observation that EGR3 is highly expressed in prostate tumours compared with normal tissue and strongly correlates with IL6 and IL8 expression in clinical samples, the present study suggests that EGR3 promotes excessive production of IL6 and IL8 observed during the progression of prostate cancer.
Pubmed
25633035
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
13
Original source reporting the Gene Disease association
BeFree,CTD_human,LHGDN
DisGENET score for the Gene Disease association
0.155678063502489
Drugs