Annotation Detail
Information
- Associated Genes
- SERPINE1
- Associated Variants
-
SERPINE1 MUTATION
SERPINE1 MUTATION - Associated Disease
- Pregnancy Complications
- Source Database
- DisGeNET
- Description
- Hereditary hypofibrinolysis, which is mediated by 4G/4G homozygosity for the PAI-1 gene, is an independent risk factor for pregnancy complications, probably acting through thrombotic induction of placental insufficiency.
- Pubmed
- 25723084
- Section of the abstract supporting the evidence
- CASE REPORT
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
Drugs