Annotation Detail

Information
Associated Genes
INS
Associated Variants
INS MUTATION
INS MUTATION
Associated Disease
polycystic ovary syndrome
Source Database
DisGeNET
Description
The results from these studies demonstrate that the well-established abnormalities in insulin action on glucose uptake and glycogen synthesis are reflected by defects in insulin signaling to these cellular processes in type 2 diabetes, obesity, and PCOS, and as expected also in inherited insulin resistance caused by a mutation in INSR.
Pubmed
25123125
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
27
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN
DisGENET score for the Gene Disease association
0.161627752473387
Drugs