Annotation Detail

Information
Associated Genes
NOTCH2
Associated Variants
NOTCH2 MUTATION
NOTCH2 MUTATION
Associated Disease
plague
Source Database
DisGeNET
Description
Based on these results, we conclude that the Notch2 receptor with PEST domain truncation enhances cell proliferation which may be associated with the activation of the Notch2 and the NF-κB signaling.
Pubmed
25314575
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs