Annotation Detail

Information
Associated Genes
MGMT
Associated Variants
MGMT MUTATION
MGMT MUTATION
Associated Disease
pituitary adenoma
Source Database
DisGeNET
Description
PRL-and GH-secreting PAs exist high expression of D2R, responding to dopamine agonists; Most PAs exist low expression of MGMT and high expression of VEGF, TMZ or bevacizumab treatment could be applied under the premise of indications.
Pubmed
25027022
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
13
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Drugs