Annotation Detail

Information
Associated Genes
ABCB1
Associated Variants
ABCB1 MUTATION
ABCB1 MUTATION
Associated Disease
Peripheral neuropathy
Source Database
DisGeNET
Description
Seventeen polymorphisms in regulatory and coding regions of genes controlling VCR targets (TUBB1, MAP4, ACTG1 and CAPG) or potentially influencing VCR levels (ABCB1 and CYP3A5) were investigated for an association with peripheral neuropathy and outcome in childhood ALL patients.
Pubmed
25084203
Section of the abstract supporting the evidence
PATIENTS & METHODS
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree,CTD_human
DisGENET score for the Gene Disease association
0.120542883744161
Drugs