Annotation Detail

Information
Associated Genes
CYP11B2
Associated Variants
CYP11B2 c.-344T>C
CYP11B2 c.-344T>C
Associated Disease
essential hypertension
Source Database
DisGeNET
Description
It has been suggested that an aldosterone synthase gene polymorphism (CYP11B2 -344T/C) is predictive of the blood pressure lowering effect of angiotensin II receptor blockers in essential hypertension.
Pubmed
16714246
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.012138939373493
Year of publication
2006
Drugs