Annotation Detail
Information
- Associated Genes
- REN
- Associated Variants
-
CYP11B2 c.-344T>C
CYP11B2 c.-344T>C - Associated Disease
- essential hypertension
- Source Database
- DisGeNET
- Description
- We examined the role of two variations of the aldosterone synthase gene (CYP11B2), one located in the promoter of the gene, T-344C, the other in the 7th exon, the T4986C (Val/Ala), on plasma levels of renin and aldosterone, blood pressure, and arterial stiffness in subjects with essential hypertension.
- Pubmed
- 9683048
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0260584197197091
- Year of publication
- 1998
Drugs