Annotation Detail
Information
- Associated Genes
- PGR
- Associated Variants
-
PGR MUTATION
PGR MUTATION - Associated Disease
- ovarian carcinoma
- Source Database
- DisGeNET
- Description
- Importantly, this BTB mediated inhibition of ER activity is selective since BTB does not suppress the activities of other nuclear receptors, including glucocorticoid receptor and progesterone receptor, suggesting that BTB functions as a selective ER signaling inhibitor with the potential to treat breast, endometrial, and ovarian cancers.
- Pubmed
- 25221777
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.0105102881410111
Drugs