Annotation Detail

Information
Associated Genes
EPHB2
Associated Variants
EPHB2 MUTATION
EPHB2 MUTATION
Associated Disease
ovarian carcinoma
Source Database
DisGeNET
Description
In conclusion, bortezomib may induce ERK phosphorylation to suppress cathepsin B and inhibit the catalytic process of autophagy in ovarian cancer and other solid tumors.
Pubmed
25375375
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00461451182536516
Drugs