Annotation Detail
Information
- Associated Genes
- ABCB1
- Associated Variants
-
ABCB1 MUTATION
ABCB1 MUTATION - Associated Disease
- osteosarcoma
- Source Database
- DisGeNET
- Description
- In conclusion, icariin possesses a reversal effect on multidrug resistance in MG-63/DOX cells through down-regulation of the MDR1 and the PI3K/Akt pathway, and has the potential to be an adjunct to chemotherapy for osteosarcoma.
- Pubmed
- 25747987
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 10
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00760037241824849
Drugs