Annotation Detail

Information
Associated Genes
MMP9
Associated Variants
MMP9 MUTATION
MMP9 MUTATION
Associated Disease
Osteoarthritis of hip
Source Database
DisGeNET
Description
Comparing to OA, aseptic loosening of TKA is associated with upregulated expression of CHIT1, IL-8 and MMP9, dysregulated RANKL:OPG ratio and low levels of inflammatory cytokines.
Pubmed
25151085
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs