Annotation Detail
Information
- Associated Genes
- ALOX5
- Associated Variants
-
ALOX5 MUTATION
ALOX5 MUTATION - Associated Disease
- Degenerative polyarthritis
- Source Database
- DisGeNET
- Description
- Our results showed that increased basal COL10A1 expression in OA hMSCs was significantly suppressed in the presence of JNK and p38 inhibitors, whereas Naproxen-induced COL10A1 expression was suppressed by 5-lipoxygenase inhibitor.
- Pubmed
- 25091567
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 12
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
Drugs