Annotation Detail

Information
Associated Genes
TNF
Associated Variants
TNF MUTATION
TNF MUTATION
Associated Disease
Degenerative polyarthritis
Source Database
DisGeNET
Description
Our study aimed to evaluate the in vitro effect of canakinumab on human osteoarthritic (OA) chondrocytes cultivated in the presence or absence of tumor necrosis factor (TNF)-α. Articular cartilage was obtained from the femoral heads of patients with osteoarthritis (OA).
Pubmed
25461395
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0318321008601061
Drugs