Annotation Detail

Information
Associated Genes
IL1B
Associated Variants
IL1B MUTATION
IL1B MUTATION
Associated Disease
Degenerative polyarthritis
Source Database
DisGeNET
Description
MiR-602 and miR-608 are important posttranscription regulators of SHH expression in OA chondrocytes, and their suppression by IL-1β may contribute to the enhanced expression of SHH and MMP-13 in OA.
Pubmed
25385442
Section of the abstract supporting the evidence
CONCLUSION
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
13
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN,RGD
DisGENET score for the Gene Disease association
0.255554621297857
Drugs