Annotation Detail
Information
- Associated Genes
- IL1B
- Associated Variants
-
IL1B MUTATION
IL1B MUTATION - Associated Disease
- Degenerative polyarthritis
- Source Database
- DisGeNET
- Description
- Moreover, the OA-related catabolic factor interleukin-1β induced the expression of Apex 2 in chondrocytes, while Apex 2 silencing using small interfering RNA reduced chondrocyte activity in vitro.
- Pubmed
- 25158232
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree,CTD_human,GAD,LHGDN,RGD
- DisGENET score for the Gene Disease association
- 0.255554621297857
Drugs