Annotation Detail

Information
Associated Genes
TLR4
Associated Variants
TLR4 MUTATION
TLR4 MUTATION
Associated Disease
obesity
Source Database
DisGeNET
Description
However, a high-fat diet activates TLR-2s, and obesity activates TLR-4s and induces spontaneous increases in serum lipopolysaccharide levels (metabolic endotoxemia).
Pubmed
25840582
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree,GAD,RGD
DisGENET score for the Gene Disease association
0.0888056920384086
Drugs