Annotation Detail

Information
Associated Genes
MAPT
Associated Variants
MAPT c.1999-6612A>G ( ENST00000344290.10, ENST00000574436.5, ENST00000535772.6, ENST00000262410.10, ENST00000415613.6, ENST00000446361.7, ENST00000571987.5, ENST00000431008.7, ENST00000351559.10, ENST00000334239.12, ENST00000420682.7, ENST00000680674.1 )
rs1768208 ( ENST00000383754.7, ENST00000415443.5, ENST00000420739.5, ENST00000428261.5, ENST00000441980.6, ENST00000447324.5, ENST00000682069.1, ENST00000684792.1 )
MAPT c.1999-6612A>G ( ENST00000262410.10, ENST00000334239.12, ENST00000344290.10, ENST00000351559.10, ENST00000415613.6, ENST00000420682.7, ENST00000431008.7, ENST00000446361.7, ENST00000535772.6, ENST00000571987.5, ENST00000574436.5, ENST00000680674.1 )
rs1768208 ( ENST00000383754.7, ENST00000415443.5, ENST00000420739.5, ENST00000428261.5, ENST00000441980.6, ENST00000447324.5, ENST00000682069.1, ENST00000684792.1 )
Associated Disease
Tauopathies
Source Database
DisGeNET
Description
Eighty-one patients with sporadic bvFTD were genotyped for tauopathy-associated SNPs at rs8070723 (microtubule-associated protein tau [MAPT]) and rs1768208 (myelin-associated oligodendrocyte basic protein [MOBP]).
Pubmed
24994843
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.208632972776538
Year of publication
2014
Drugs