Annotation Detail

Information
Associated Genes
TNPO3
Associated Variants
TNPO3 SNV
TNPO3 c.2164-1477T>G ( ENST00000265388.10, ENST00000471166.1, ENST00000471234.5, ENST00000482320.5, ENST00000627585.2 )
TNPO3 c.2164-1477T>C ( ENST00000265388.10, ENST00000471166.1, ENST00000471234.5, ENST00000482320.5, ENST00000627585.2 )
TNPO3 SNV
TNPO3 c.2164-1477T>G ( ENST00000265388.10, ENST00000471166.1, ENST00000471234.5, ENST00000482320.5, ENST00000627585.2 )
TNPO3 c.2164-1477T>C ( ENST00000265388.10, ENST00000471166.1, ENST00000471234.5, ENST00000482320.5, ENST00000627585.2 )
Associated Disease
Lupus Erythematosus, Systemic
Source Database
DisGeNET
Description
[We identified and then confirmed through replication two new genetic loci for SLE: a promoter-region allele associated with reduced expression of BLK and increased expression of C8orf13 and variants in the ITGAM-ITGAX region.]
Pubmed
18204098
Original source reporting the Gene Disease association
GAD
DisGENET score for the Gene Disease association
0.129739569786488
Year of publication
2008
Drugs