Annotation Detail
Information
- Associated Genes
- IL1A
- Associated Variants
-
IL1A MUTATION
IL1A MUTATION
IL1A p.Ala114Ser (p.A114S) ( ENST00000263339.4 )
IL1A p.Ala114Ser (p.A114S) ( ENST00000263339.4 ) - Associated Disease
- breast carcinoma
- Source Database
- DisGeNET
- Description
- Assuming a dominant genetic model, IL1A A114S significantly modified the dose-response relationship between cumulative personal diagnostic radiation and breast cancer risk, adjusted for occupational dose (P(interaction) = 0.004).
- Pubmed
- 17932347
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00434306995328485
- Year of publication
- 2007
Drugs