Annotation Detail

Information
Associated Genes
ABCG2
Associated Variants
ABCG2 MUTATION
ABCG2 MUTATION
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
Resistant cells expressed higher levels of genes coding for cancer stem cell markers (JARID1B, CD271 and Fibronectin) as well as genes involved in drug resistance (ABCG2), cell invasion and promotion of metastasis (MMP-1 and MMP-2).
Pubmed
25725450
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00217153497664243
Drugs