Annotation Detail

Information
Associated Genes
PIK3CB
Associated Variants
PIK3CB MUTATION
PIK3CB MUTATION
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
In conclusion, this study suggested that EMT process can be triggered by the BMP2/BMPR axis in gastric cancer and then involved in the tumor cell migration, invasion, and metastasis via the activation of PI3K/AKT and MEK/ERK pathways.
Pubmed
25448881
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0149293029644167
Drugs