Annotation Detail

Information
Associated Genes
JUN
Associated Variants
JUN MUTATION
JUN MUTATION
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
Our results suggest that the AP-1/miR-101 feedback loop may prevent the excessive activation of metastatic signals imposed by ERK2/AP-1 and highlight the biological significance of miR-101 downregulation in cancer metastasis.
Pubmed
25260594
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,LHGDN
DisGENET score for the Gene Disease association
0.00707735171741616
Drugs