Annotation Detail

Information
Associated Genes
CDH1
Associated Variants
CDH1 MUTATION
CDH1 MUTATION
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
The de-regulation of both of miR-29b/c and DNMT3A leads to the epigenetic silencing of CDH1 and contributes to the metastasis phenotype in GC.
Pubmed
25874772
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
11
Original source reporting the Gene Disease association
BeFree,CTD_human,LHGDN
DisGENET score for the Gene Disease association
0.176880324089745
Drugs