Annotation Detail
Information
- Associated Genes
- CDH1
- Associated Variants
-
CDH1 MUTATION
CDH1 MUTATION - Associated Disease
- Neoplasm Metastasis
- Source Database
- DisGeNET
- Description
- We highlighted the importance of nuclear HIF-1α in the biology of metastasis for the mesenchymal-epithelial transition: this phenotype was regulated by Wwox plus hypoxia through E-cadherin target gene, playing a pivotal role in bone metastasis colonization.
- Pubmed
- 25447306
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 11
- Original source reporting the Gene Disease association
- BeFree,CTD_human,LHGDN
- DisGENET score for the Gene Disease association
- 0.176880324089745
Drugs