Annotation Detail

Information
Associated Genes
IL23R
Associated Variants
IL23R MUTATION
IL23R MUTATION
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
In colorectal cancer, elevated expression of IL-23, IL-23 receptor and IL-17A has been linked to adverse prognostic outcome and rapid progression to metastatic disease.
Pubmed
26457610
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs