Annotation Detail

Information
Associated Genes
NQO1
Associated Variants
NQO1 MUTATION
NQO1 MUTATION
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
Clinically, overexpression of the NFE2L2 target gene NQO1 in tumours was significantly associated with metastasis, vascular invasion, the adverse prognostic C2 gene signature, as well as poor outcome.
Pubmed
25135868
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Drugs