Annotation Detail

Information
Associated Genes
SPINK1
Associated Variants
SPINK1 p.Asn34Ser (p.N34S) ( ENST00000510027.2, ENST00000296695.10 )
SPINK1 p.Asn34Ser (p.N34S) ( ENST00000296695.10, ENST00000510027.2 )
Associated Disease
acute pancreatitis
Source Database
DisGeNET
Description
Mutation p.N34S in SPINK1 may predispose patients to acute pancreatitis, especially in those abusing alcohol, and may promote a more severe course of the disease.
Pubmed
26100556
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00698154380396719
Year of publication
2015
Drugs