Annotation Detail
Information
- Associated Genes
- APOA1
- Associated Variants
-
APOA1 MUTATION
APOA1 MUTATION - Associated Disease
- myocardial infarction
- Source Database
- DisGeNET
- Description
- Bioinformatic analysis of this differential gene-set for associated pathways revealed 1) increasing disease severity in AMI patients is associated with a decreased expression of genes involved in the developmental epithelial-to-mesenchymal transition pathway, and 2) modulation of cholesterol transport genes that include ABCA1, CETP, APOA1, and LDLR is associated with clinical outcome.
- Pubmed
- 24801707
- Section of the abstract supporting the evidence
- METHODS AND RESULTS
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.0330909592636486
Drugs