Annotation Detail
Information
- Associated Genes
- CALR
- Associated Variants
-
CALR MUTATION
CALR MUTATION - Associated Disease
- Myeloproliferative disease
- Source Database
- DisGeNET
- Description
- Myeloproliferative neoplasms (MPNs) are stem cell-derived clonal myeloid malignancies characterized by a unique somatic mutational profile since three mutually exclusive mutations (JAK2V617F, MPL, and CALR) sustain the great majority of the cases.
- Pubmed
- 25139710
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00542883744160607
Drugs