Annotation Detail

Information
Associated Genes
TLR4
Associated Variants
TLR4 MUTATION
TLR4 MUTATION
Associated Disease
myasthenia gravis
Source Database
DisGeNET
Description
We observed that TLR4 stimulation led to a more pronounced Teff activatory status, suggesting that TLR4 signaling in MG thymic milieu may affect cell-to-cell interactions, favoring autoreactive T-cell activation.
Pubmed
24397961
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,LHGDN
DisGENET score for the Gene Disease association
0.00326723398662778
Drugs