Annotation Detail
Information
- Associated Genes
- TNF
- Associated Variants
-
NC_000002.12:g.112837290A>G
TNF c.-488G>A
IL6 c.-84-153C>G ( ENST00000404625.5 )
NC_000002.12:g.112837290A>G
TNF c.-488G>A
IL6 c.-84-153C>G ( ENST00000404625.5 ) - Associated Disease
- Depressive Symptoms
- Source Database
- DisGeNET
- Description
- The aim of the present study was to investigate a trio of functional SNPs in the promoter regions of IL6 (-174G>C, rs1800795), IL1β (-511C>T, rs16944), and TNF (-308G>A, rs1800629) as moderators of the relationship between chronic stress exposure and elevations in depressive symptoms.
- Pubmed
- 25596176
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00108576748832121
- Year of publication
- 2015
Drugs