Annotation Detail

Information
Associated Genes
MPO
Associated Variants
NC_000017.11:g.58281401C>T
rs2794520
NC_000002.12:g.112837290A>G
TNF c.-1037C>T
IL6 c.-85+369G>C ( ENST00000404625.5 )
NC_000017.11:g.58281401C>T
rs2794520
NC_000002.12:g.112837290A>G
TNF c.-1037C>T
IL6 c.-85+369G>C ( ENST00000404625.5 )
Associated Disease
Malignant neoplasm of lung
Source Database
DisGeNET
Description
We evaluated the role of tumor necrosis factor α (TNFA) rs1799724, interleukin 1β (IL1B) rs16944, IL6 rs1800796, myeloperoxidase (MPO) rs2333227 and C-reactive protein (CRP) rs2794520 in a case-control study comprised of 462 lung cancer cases and 379 controls in a Japanese population.
Pubmed
24139238
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0778729510301892
Year of publication
2013
Drugs