Annotation Detail
Information
- Associated Genes
- PPIAP10
- Associated Variants
-
IL6R c.-208G>A
(
ENST00000368485.8,
ENST00000344086.8,
ENST00000622330.5 )
IL6R c.1067-700C>T ( ENST00000344086.8, ENST00000368485.8 )
IL6R p.Asp358Ala (p.D358A) ( ENST00000368485.8, ENST00000344086.8 )
IL6R p.Asp358Val (p.D358V) ( ENST00000368485.8, ENST00000344086.8 )
rs3091244
rs3091244
rs2794521
NC_000002.12:g.112837290A>G
IL6 c.-84-153C>G ( ENST00000404625.5 )
IL6R c.-208G>A ( ENST00000344086.8, ENST00000368485.8, ENST00000622330.5 )
IL6R c.1067-700C>T ( ENST00000344086.8, ENST00000368485.8 )
IL6R p.Asp358Ala (p.D358A) ( ENST00000344086.8, ENST00000368485.8 )
IL6R p.Asp358Val (p.D358V) ( ENST00000344086.8, ENST00000368485.8 )
rs3091244
rs3091244
rs2794521
NC_000002.12:g.112837290A>G
IL6 c.-84-153C>G ( ENST00000404625.5 ) - Associated Disease
- Fatigue
- Source Database
- DisGeNET
- Description
- The associations between fatigue and SNPs in inflammation-related genes; IL1β (rs16944), IL6 (rs1800795), IL6receptor (rs4129267, rs4845617, rs2228145), CRP (rs2794521, rs3091244) were investigated, together with the relations between SNPs in IL6R,IL1β and CRP genes and mRNA blood expression levels of IL6R and IL1β and serum hsCRP-levels, respectively.
- Pubmed
- 21496483
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2011
Drugs