Annotation Detail
Information
- Associated Genes
- MGMT
- Associated Variants
-
MGMT c.-28C>T
(
ENST00000651593.1,
ENST00000306010.8 )
MGMT c.-28C>T ( ENST00000306010.8, ENST00000651593.1 ) - Associated Disease
- glioblastoma
- Source Database
- DisGeNET
- Description
- The T genotype of the MGMT C>T (rs16906252) enhancer single-nucleotide polymorphism (SNP) is associated with promoter methylation and longer survival in glioblastoma patients.
- Pubmed
- 22975219
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.20179726836621
- Year of publication
- 2013
Drugs