Annotation Detail

Information
Associated Genes
MGMT
Associated Variants
MGMT c.-28C>T ( ENST00000651593.1, ENST00000306010.8 )
MGMT c.-28C>T ( ENST00000306010.8, ENST00000651593.1 )
Associated Disease
adenocarcinoma
Source Database
DisGeNET
Description
The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas.
Pubmed
21355081
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0147972762675036
Year of publication
2011
Drugs