Annotation Detail

Information
Associated Genes
VEGFA
Associated Variants
POLR1C c.945+240822A>G
POLR1C c.945+240822A>G
Associated Disease
Glomerulonephritis, Minimal Change
Source Database
DisGeNET
Description
Finally, we have not proved any significant influence of the polymorphisms at positions -2578 C/A and -1154 G/A of the vascular endothelial growth factor gene promoter on the progression of chronic glomerulonephritides even though our study suggests a negative effect of CC genotype of -2578 C/A polymorphism on the clinical course of minimal change disease/focal segmental glomerulosclerosis.
Pubmed
21978756
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2011
Drugs