Annotation Detail

Information
Associated Genes
BHLHE40
Associated Variants
CSNK1E c.737-160A>G, TPTEP2-CSNK1E c.737-160A>G ( ENST00000359867.7, ENST00000396832.6, ENST00000403904.5, ENST00000405675.7, ENST00000413574.6, ENST00000400206.7 )
rs6442925
TMEM165 c.793-485A>G ( ENST00000381334.10, ENST00000506198.5 )
CSNK1E c.737-160A>G, TPTEP2-CSNK1E c.737-160A>G ( ENST00000359867.7, ENST00000396832.6, ENST00000403904.5, ENST00000405675.7, ENST00000413574.6, ENST00000400206.7 )
rs6442925
TMEM165 c.793-485A>G ( ENST00000381334.10, ENST00000506198.5 )
Associated Disease
bipolar disorder
Source Database
DisGeNET
Description
A multi-locus interaction between rs6442925 in the 5' upstream of BHLHB2, rs1534891 in CSNK1E, and rs534654 near the 3' end of the CLOCK gene, however, is significantly associated with BP (P = 0.00000172).
Pubmed
18228528
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00500550582928437
Year of publication
2008
Drugs