Annotation Detail

Information
Associated Genes
KCNQ1
Associated Variants
KCNQ1 p.Val205Met (p.V205M) ( ENST00000713725.1, ENST00000335475.6, ENST00000646564.2, ENST00000155840.12, ENST00000496887.7 )
KCNQ1 p.Val205Met (p.V205M) ( ENST00000155840.12, ENST00000335475.6, ENST00000496887.7, ENST00000646564.2, ENST00000713725.1 )
Associated Disease
long QT syndrome
Source Database
DisGeNET
Description
Two First Nations communities in northern British Columbia are affected disproportionately with LQTS largely due to the V205M mutation in KCNQ1, however, the pathology and phenotypic expression for those V205M homozygous has been unknown.
Pubmed
23844633
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.41651083741347
Year of publication
2013
Drugs