Annotation Detail

Information
Associated Genes
VEGFA
Associated Variants
VEGFA MUTATION
VEGFA MUTATION
Associated Disease
Malignant neoplasm of stomach
Source Database
DisGeNET
Description
In addition, ramucirumab, a monoclonal antibody targeting vascular endothelial growth factor receptor (VEGFR)-2, is the first biological treatment that showed survival benefits as a single-agent therapy in patients with advanced GC who progressed after first-line chemotherapy.
Pubmed
24744582
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0286209487002708
Drugs