Annotation Detail

Information
Associated Genes
MAPK1
Associated Variants
MAPK1 MUTATION
MAPK1 MUTATION
Associated Disease
Malignant neoplasm of stomach
Source Database
DisGeNET
Description
Deactivation of phosphorylation of ERK protein is one of the mechanisms of sorafenib inhibiting gastric cancer.
Pubmed
25136776
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00868613990656971
Drugs