Annotation Detail
Information
- Associated Genes
- TYMS
- Associated Variants
-
TYMS MUTATION
TYMS MUTATION - Associated Disease
- Malignant neoplasm of stomach
- Source Database
- DisGeNET
- Description
- These polymorphisms have been related to the risk of suffering different cancers, for example leukemia, breast or gastric cancer, and response to different drugs, among which are methotrexate glutamates, stavudine, and specifically 5-fluorouracil (5-FU), as TYMS is its direct target.
- Pubmed
- 26166093
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.043800625581681
Drugs