Annotation Detail
Information
- Associated Genes
- PIK3CB
- Associated Variants
-
PIK3CB MUTATION
PIK3CB MUTATION - Associated Disease
- Malignant neoplasm of stomach
- Source Database
- DisGeNET
- Description
- Mechanically, PTP1B promotes gastric cancer cell proliferation, survival and invasiveness through modulating Src-related signaling pathways, such as Src/Ras/MAPK and Src/phosphatidylinositol-3-kinase (PI3K)/Akt pathways.
- Pubmed
- 25590580
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0103147911390515
Drugs