Annotation Detail

Information
Associated Genes
ERCC1
Associated Variants
POLR1G p.Pro40Ser (p.P40S) ( ENST00000309424.8, ENST00000589804.1 )
POLR1G p.Pro40Ser (p.P40S) ( ENST00000309424.8, ENST00000589804.1 )
Associated Disease
Non-small cell lung carcinoma
Source Database
DisGeNET
Description
These findings suggest that ERCC1 C118T polymorphisms may serve as a biomarker for lung cancer risk and have prognostic value in patients with advanced non-small cell lung cancer (NSCLC) undergoing platinum-based treatment.
Pubmed
23727606
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.15629726598864
Year of publication
2013
Drugs