Annotation Detail
Information
- Associated Genes
- ERCC1
- Associated Variants
-
POLR1G p.Pro40Ser (p.P40S)
(
ENST00000309424.8,
ENST00000589804.1 )
POLR1G p.Pro40Ser (p.P40S) ( ENST00000309424.8, ENST00000589804.1 ) - Associated Disease
- squamous cell carcinoma
- Source Database
- DisGeNET
- Description
- Subgroup analysis revealed that ERCC1 118 C/T or T/T was associated with increased survival in elderly patients (P=0.018), male (P=0.022), squamous carcinoma (P=0.003), smoker (P=0.076) and those treated with non-gemcitabine/cisplatin or carboplatin (non-GP/GC) regimen (P=0.023).
- Pubmed
- 21676483
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00481000882732476
- Year of publication
- 2012
Drugs