Annotation Detail

Information
Associated Genes
MRTFA
Associated Variants
MRTFA MUTATION
MRTFA MUTATION
Associated Disease
Lupus Erythematosus, Systemic
Source Database
DisGeNET
Description
Aggregation of plasmacytoid DCs in the splenic perifollicular region, follicular translocation of MZ B cells, and loss of MKL1 and MZMs were also observed in an additional murine lupus model and in the spleens of patients with SLE.
Pubmed
26098211
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs