Annotation Detail

Information
Associated Genes
TNF
Associated Variants
TNF MUTATION
TNF MUTATION
Associated Disease
Lupus Vulgaris
Source Database
DisGeNET
Description
Since chronic local activation of proinflammatory cytokines including TNF-α in resident renal cells may exist in patients with active lupus, synergistic effect of TNF-α and pseudoviral infection is possibly involved in the development of LN.
Pubmed
24627031
Section of the abstract supporting the evidence
CONCLUSION
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00826280829424801
Drugs