Annotation Detail
Information
- Associated Genes
- NTRK2
- Associated Variants
-
BDNF p.Val148Met (p.V148M)
(
ENST00000532997.5,
ENST00000395981.7,
ENST00000356660.9,
ENST00000314915.6,
ENST00000439476.6,
ENST00000530861.5,
ENST00000395983.7,
ENST00000395986.6,
ENST00000525950.5,
ENST00000533246.5,
ENST00000418212.5,
ENST00000525528.1,
ENST00000533131.5,
ENST00000395978.7,
ENST00000438929.5 )
NTRK2 c.2173-18050G>A ( ENST00000277120.8, ENST00000323115.11, ENST00000376213.6, ENST00000686259.1, ENST00000686324.1, ENST00000686496.1, ENST00000687386.1, ENST00000689301.1, ENST00000691788.1, ENST00000692181.1, ENST00000692473.1 )
NTRK2 c.*4284A>G ( ENST00000277120.8, ENST00000323115.11, ENST00000376213.6, ENST00000686259.1, ENST00000686324.1, ENST00000686496.1, ENST00000687386.1, ENST00000689301.1, ENST00000691788.1, ENST00000692181.1, ENST00000692473.1 )
rs2769605
BDNF p.Val148Met (p.V148M) ( ENST00000314915.6, ENST00000356660.9, ENST00000395978.7, ENST00000395981.7, ENST00000395983.7, ENST00000395986.6, ENST00000418212.5, ENST00000438929.5, ENST00000439476.6, ENST00000525528.1, ENST00000525950.5, ENST00000530861.5, ENST00000532997.5, ENST00000533131.5, ENST00000533246.5 )
NTRK2 c.2173-18050G>A ( ENST00000277120.8, ENST00000323115.11, ENST00000376213.6, ENST00000686259.1, ENST00000686324.1, ENST00000686496.1, ENST00000687386.1, ENST00000689301.1, ENST00000691788.1, ENST00000692181.1, ENST00000692473.1 )
NTRK2 c.*4284A>G ( ENST00000277120.8, ENST00000323115.11, ENST00000376213.6, ENST00000686259.1, ENST00000686324.1, ENST00000686496.1, ENST00000687386.1, ENST00000689301.1, ENST00000691788.1, ENST00000692181.1, ENST00000692473.1 )
rs2769605 - Associated Disease
- major depressive disorder
- Source Database
- DisGeNET
- Description
- To examine whether the polymorphisms of BDNF (rs6265) and NTRK2 (rs1387923, rs2769605 and rs1565445) genes confer risk for TRD in major depressive disorder (MDD), a total of 948 MDD patients were recruited in a 12-week, multicenter, prospective longitudinal study.
- Pubmed
- 23137999
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00190009310456212
- Year of publication
- 2013
Drugs