Annotation Detail
Information
- Associated Genes
- NTRK2
- Associated Variants
-
AGPAT4 c.179-21567A>G
(
ENST00000320285.9,
ENST00000366905.3,
ENST00000366911.9 )
NTRK2 c.2173-18050G>A ( ENST00000277120.8, ENST00000323115.11, ENST00000376213.6, ENST00000686259.1, ENST00000686324.1, ENST00000686496.1, ENST00000687386.1, ENST00000689301.1, ENST00000691788.1, ENST00000692181.1, ENST00000692473.1 )
NTRK2 c.*4284A>G ( ENST00000277120.8, ENST00000323115.11, ENST00000376213.6, ENST00000686259.1, ENST00000686324.1, ENST00000686496.1, ENST00000687386.1, ENST00000689301.1, ENST00000691788.1, ENST00000692181.1, ENST00000692473.1 )
AGPAT4 c.179-21567A>G ( ENST00000320285.9, ENST00000366905.3, ENST00000366911.9 )
NTRK2 c.2173-18050G>A ( ENST00000277120.8, ENST00000323115.11, ENST00000376213.6, ENST00000686259.1, ENST00000686324.1, ENST00000686496.1, ENST00000687386.1, ENST00000689301.1, ENST00000691788.1, ENST00000692181.1, ENST00000692473.1 )
NTRK2 c.*4284A>G ( ENST00000277120.8, ENST00000323115.11, ENST00000376213.6, ENST00000686259.1, ENST00000686324.1, ENST00000686496.1, ENST00000687386.1, ENST00000689301.1, ENST00000691788.1, ENST00000692181.1, ENST00000692473.1 ) - Associated Disease
- post-traumatic stress disorder
- Source Database
- DisGeNET
- Description
- Using q-value analysis for multiplicity correction, we found significant interactions between lithium response and SNPs (rs1387923 and rs1565445) in the gene encoding neurotrophic tyrosine kinase receptor type 2 (NTRK2) and suicidal ideation, and between SNP rs2064721 in the gene encoding inositol polyphosphate-1-phosphatase (INPP1) and post-traumatic stress disorder.
- Pubmed
- 17570738
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0802714418720803
- Year of publication
- 2007
Drugs